CERVICAL CHLAMYDIA-TRACHOMATIS INFECTION IN UNIVERSITY WOMEN - RELATIONSHIP TO HISTORY, CONTRACEPTION, ECTOPY, AND CERVICITIS
CERVICAL CHLAMYDIA-TRACHOMATIS INFECTION IN UNIVERSITY WOMEN - RELATIONSHIP TO HISTORY, CONTRACEPTION, ECTOPY, AND CERVICITIS
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DOI：
10.1016/s0002-9378(85)80105-8
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发表时间：
1985-01-01
影响因子：
9.8
通讯作者：
ALEXANDER, ER
中科院分区：
文献类型：
--
作者：
HARRISON, HR;COSTIN, M;ALEXANDER, ER
162名大学生中13人宫颈沙眼衣原体感染，感染率为8%。感染与年轻年龄相关（p < 0.05），4年的性生活（p < 0.05），淋病史（p < 0.01），与患有尿道炎的伴侣接触（p < 0.01）。使用宫内避孕或屏障避孕的妇女感染率（2%）低于使用口服避孕的妇女（14.3%，p < 0.05）或根本没有感染的妇女（10.7%，p < 0.05）。感染与宫颈炎评分密切相关，宫颈炎评分由红斑、异位、分泌物和含有白色血细胞的分泌物计算（p < 0.0001）。通过多变量分析，提出了一种临床方法，用于检测所有未使用屏障避孕的宫颈炎妇女的衣原体微生物。该方法对衣原体感染的阳性预测值为28%，阴性预测值为98.4%。使用口服避孕药的妇女宫颈异位增加（p < 0.01），异位妇女感染增加，无论其避孕方法如何（p < 0.001）。这些结果将有助于更快地诊断宫颈内衣原体感染，并在年轻妇女和高流行率群体的避孕选择。
Endocervical Chlamydia trachomatis infection was found in 13 of 162 volunteer female university students (8%). Infection was correlated with younger age (p < 0.05), .ltoreq. 4 years of intercourse (p < 0.05), a history of gonorrhea (p < 0.01), and exposure to a partner with urethritis (p < 0.01). Women who used intrauterine or barrier contraception had less infection (2%) than did women who used oral contraception (14.3%, p < 0.05) or none at all (10.7%, p < 0.05). Infection was strongly associated with a cervicitis score calculated from erythema, ectopy, discharge, and secretions that contained white blood cells (p < 0.0001). By multivariate analysis, a proposed clinical approach was arrived at for testing for chlamydial organisms all women with cervicitis who were not using barrier contraception. The positive predictive value of this approach for chlamydial infection was 28%, and the negative predictive value 98.4%. Cervical ectopy was increased in women who used oral contraception (p < 0.01), and infection was increased in women with ectopy, regardless of their contraceptive method (p < 0.001). These results will aid in more rapid diagnosis of endocervical chlamydial infection and in the choice of contraception in young women and high-prevalence groups.