Work rehabilitation in schizophrenia: Does cognitive impairment limit improvement?
Work rehabilitation in schizophrenia: Does cognitive impairment limit improvement?
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DOI：
10.1093/oxfordjournals.schbul.a006873
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发表时间：
2001-01-01
影响因子：
6.6
通讯作者：
Bryson, G
中科院分区：
文献类型：
--
作者：
Bell, MD;Bryson, G
认知障碍可能是导致精神分裂症残疾的一个重要因素，并可能限制工作康复的改善速度。对参加为期 6 个月的工作康复计划的 33 名精神分裂症或分裂情感障碍门诊患者进行了症状严重程度评估，并在入院时进行了神经心理学测试。使用工作行为量表每两周评估一次他们的工作表现。在 5 个工作表现领域中，76% 至 91% 的受试者在 26 周内达到熟练程度或显着提高。改善率的个体差异可以通过神经心理学变量进行稳健预测：工作习惯，r(2) = 0.79；个人陈述，r(2) = 0.73；合作性，r(2) = 0.67；工作质量，r(2) = 0.56；社交技能，r(2) = 0.27；总计，r(2) = 0.44，神经心理学测量与工作领域具有不同的关系。改善的个体差异不能通过症状测量来预测。这些发现将认知障碍与残疾联系起来，并表明补救或适应此类缺陷可能是成功康复所必需的。
Cognitive impairments may be an important contributor to disability in schizophrenia and may limit the rate of improvement in work rehabilitation, Thirty-three outpatients with schizophrenia or schizoaffective disorder who participated in a 6-month work rehabilitation program were assessed for symptom severity and administered neuropsychological testing at intake, Their work performance was evaluated biweekly using the Work Behavior Inventory. On each of five domains of work performance, 76 to 91 percent of subjects reached proficiency or improved significantly over 26 weeks. Individual differences in rate of improvement were robustly predicted by neuropsychological variables: Work Habits, r(2) = 0.79; Personal Presentation, r(2) = 0.73; Cooperativeness, r(2) = 0.67; Work Quality, r(2) = 0.56; Social Skills, r(2) = 0.27; Total, r(2) = 0.44, Neuropsychological measures had differential relationships to work domains. Individual differences in improvement were not predicted by symptom measures. These findings link cognitive impairment to disability and suggest that remediating or accommodating such deficits may be necessary for successful rehabilitation.