Regioselective fabrication of gold nanowires using open-space laminar flow for attomolar protein detection
Regioselective fabrication of gold nanowires using open-space laminar flow for attomolar protein detection
复制标题
使用开放空间层流区域选择性制造金纳米线用于阿托摩尔蛋白质检测
DOI：
10.1039/d2cc00507g
复制
发表时间：
2022
影响因子：
4.9
通讯作者：
Uchiyama Katsumi
中科院分区：
文献类型：
--
作者：
Nishitani Yuki;Kasai Nahoko;Nakajima Hizuru;Kato Shungo;Mao Sifeng;Uchiyama Katsumi
金纳米线具有高稳定性和生物相容性等优点，有望应用于生物传感领域。然而，在没有特殊要求的环境下，在精确的位置上制备单一的金纳米线仍然是不方便的。在这项研究中，我们提出了一种开放空间层流方法，在正常条件下在精确的位置制备单一的金纳米线。所制备的金纳米线对IgA具有良好的生物传感性能，检测下限极低(凌晨1点)。
Gold nanowires are expected to be applied to biosensing due to their advantages, such as high stability and biocompatibility. However, it is still inconvenient to fabricate a single gold nanowire at a precise position, and without a special demanding environment. In this study, we present an open-space laminar flow approach for fabricating a single gold nanowire at a precise position under normal conditions. The fabricated gold nanowire demonstrated excellent biosensing of IgA with an extremely low limit of detection (1 aM).