EXPERIMENTAL RETINECTOMY IN THE RABBIT
EXPERIMENTAL RETINECTOMY IN THE RABBIT
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兔子实验性视网膜切除术
DOI：
10.1097/00006982-199001010-00014
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Brian Morin
中科院分区：
文献类型：
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作者：
R. Hutchins;D. D’Amico;VO;Brian Morin
我们建立了一个模型，在有晶状体眼进行不同大小的视网膜切除术，并检测视网膜附着、视网膜前膜形成和眼压的影响。11只视网膜切除眼，平均缺损区5.6个视盘面积，术后随访48~62d，无视网膜固定术，视网膜切除边缘可见色素瘢痕，累及感光细胞/视网膜色素上皮层。检眼镜或组织学检查均未发现视网膜前膜形成的征象。视网膜切除术后的眼压与未手术的对照眼相似。这项在无血管兔视网膜上的实验研究表明，视网膜切除术并不一定会导致视网膜前膜或眼压降低。
We developed a model for creating retinectomies of various sizes in phakic rabbit eyes and examined the effects of retinal attachment, epiretinal membrane formation, and intraocular pressure. Eleven retinectomized eyes with an average defect size of 5.6 disc areas and a postoperative followup from 48 to 62 days remained attached without retinopexy, and pigmented scarring involving the photoreceptor/retinal pigment epithelial layers was observed at the margins of the retinectomy. No sign of epiretinal membrane formation was detected by ophthalmoscopic or histologic examination. Postoperative ocular tensions were similar between retinectomized and unoperated control eyes. This experimental study in the avascular rabbit retina suggests that retinectomies do not invariably cause epiretinal membranes or ocular hypotension.