Memory Load Alters Perception-Related Neural Oscillations during Multisensory Integration
Memory Load Alters Perception-Related Neural Oscillations during Multisensory Integration
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DOI：
10.1523/jneurosci.1397-20.2020
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发表时间：
2021-02-17
影响因子：
5.3
通讯作者：
Keil, Julian
中科院分区：
文献类型：
--
作者：
Michail, Georgios;Senkowski, Daniel;Keil, Julian
整合不同感官的信息是人类感知的中心特征。以前的研究表明，多感觉整合是由刺激驱动的自下而上和自上而下的内源性影响之间的上下文依赖和很大程度上自适应的相互作用形成的。一个关键的问题是，这种相互作用对可用认知资源的数量有多敏感。在本研究中，我们通过测量健康受试者的高密度脑电(EEG)来考察有限的认知资源对视听整合的影响。在双任务设计中，受试者分别被试进行声诱发闪光错觉(SIFI)和言语n-back任务(0-back，低负荷和2-back，高负荷)。在SIFI中，一个闪光和两个快速嘟嘟声的结合可以诱导出两个闪光的错觉。我们发现，与低负荷相比，高负荷增加了错觉易感性，并调制了与错觉相关的跨通道交互作用下的神经振荡。高负荷下的错觉知觉与听觉和运动区早期β功率的降低(18-26赫兹，类似于70ms)有关，可能反映了早期失配信号和随后的自上而下的影响，包括中前扣带回皮质(ACC)的额叶theta功率(7-9赫兹，类似于120ms)的增加，以及后来额叶和听觉皮质的β功率抑制(13-22赫兹，类似于350ms)。我们的研究表明，支持SIFI的整合性跨通道交互作用对可用认知资源的数量敏感，当认知资源稀缺时，多感觉整合参与自上而下的theta和beta振荡。
Integrating information across different senses is a central feature of human perception. Previous research suggests that multisensory integration is shaped by a context-dependent and largely adaptive interplay between stimulus-driven bottom-up and top-down endogenous influences. One critical question concerns the extent to which this interplay is sensitive to the amount of available cognitive resources. In the present study, we investigated the influence of limited cognitive resources on audiovisual integration by measuring high-density electroencephalography (EEG) in healthy participants performing the soundinduced flash illusion (SIFI) and a verbal n-back task (0-back, low load and 2-back, high load) in a dual-task design. In the SIFI, the integration of a flash with two rapid beeps can induce the illusory perception of two flashes. We found that high compared with low load increased illusion susceptibility and modulated neural oscillations underlying illusion-related crossmodal interactions. Illusion perception under high load was associated with reduced early beta power (18-26 Hz, similar to 70 ms) in auditory and motor areas, presumably reflecting an early mismatch signal and subsequent top-down influences including increased frontal theta power (7-9 Hz, similar to 120 ms) in mid-anterior cingulate cortex (ACC) and a later beta power suppression (13-22 Hz, similar to 350 ms) in prefrontal and auditory cortex. Our study demonstrates that integrative crossmodal interactions underlying the SIFI are sensitive to the amount of available cognitive resources and that multisensory integration engages top-down theta and beta oscillations when cognitive resources are scarce.