Electronic medical records and personalized medicine

Electronic medical records and personalized medicine
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DOI:
10.1007/s00439-011-0992-y
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发表时间:
2011-07-01
期刊:
影响因子:
5.3
通讯作者:
Williams, Marc S.
Williams, Marc S.
中科院分区:
生物学2区
文献类型:
--
作者:
Hoffman, Mark A.;Williams, Marc S.

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如果要实现个性化医疗的梦想,就必须捕获、合成每个人特定的海量数据,并在需要这些信息为患者做出护理决策时提供给临床医生。这只能通过使用为支持这一功能而设计的复杂的电子病历(EMR)系统来实现。本文将定义全功能EMR的两个重要方面:在护理点向患者或临床医生提供高质量的特定背景信息的能力(所谓的“即时”教育)和结合来自不同来源的临床相关信息的能力,以便指导临床医生对给定患者进行优化干预(临床决策支持)。个人化的医学例子被用来说明这些概念。在实施时,大多数电子病历系统没有被用来吸收提供个性化医疗所需的信息。提供了对当前可用的系统的必要增强的描述,这些系统将需要创建一个“支持个性化医疗”的EMR。
If the dream of personalized medicine is to be realized, tremendous amounts of data specific to each individual must be captured, synthesized and presented to clinicians at the time this information is needed to make care decisions for the patient. This can only be accomplished through the use of sophisticated electronic medical record (EMR) systems that are designed to support this function. This article will define two important aspects of a fully functional EMR the ability to: present patients or clinicians with high quality context specific information at the point of care (so-called "just-in time" education) and to combine clinically relevant information from disparate sources in order to guide the clinician to the optimized intervention for a given patient (clinical decision support). Personalized medicine examples are used to illustrate these concepts. As implemented most EMR systems are not being used to assimilate the information needed to provide personalized medicine. A description of necessary enhancements to currently available systems that will be needed to create a "personalized medicine enabled" EMR is provided.