Prevalence of symptoms of asthma, rhinitis and eczema in 13-to 14-year-old children in Africa: the International Study of Asthma and Allergies in Childhood Phase III
Prevalence of symptoms of asthma, rhinitis and eczema in 13-to 14-year-old children in Africa: the International Study of Asthma and Allergies in Childhood Phase III
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DOI：
10.1111/j.1398-9995.2007.01325.x
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发表时间：
2007-03-01
期刊：
影响因子：
12.4
通讯作者：
Zar, H. J.
中科院分区：
文献类型：
--
作者：
Ait-Khaled, N.;Odhiambo, J.;Zar, H. J.
国际儿童哮喘和过敏研究的第一阶段提供了关于哮喘、过敏性鼻结膜炎和湿疹发展的国际流行模式和潜在危险因素的宝贵信息。但是，在第一阶段，只涉及六个非洲国家（阿尔及利亚、突尼斯、摩洛哥、肯尼亚、南非和埃塞俄比亚）。5-6年后进行的第三阶段在16个国家招募了22个中心，包括第一阶段参与的大多数中心以及摩洛哥、突尼斯、刚果民主共和国、多哥、苏丹、喀麦隆、加蓬、留尼汪岛和南非的新中心。在非洲各中心之间，这三种疾病的主要症状的患病率存在相当大的差异：喘息（4.0-21.5%）、过敏性鼻结膜炎（7.2-27.3%）和湿疹（4.7-23.0%）。在不同国家之间和同一国家的不同中心之间都有很大的差异。包括开普敦（20.3%）、波洛克瓦内（18.0%）、留尼旺岛（21.5%）、布拉柴维尔（19.9%）、内罗毕（18.0%）、科特迪瓦城市（19.3%）和科纳克里（18.6%）在内的几个中心显示出相对较高的哮喘症状患病率，与西欧相似。还有一些中心显示过敏性鼻结膜炎（开普敦、留尼旺岛、布拉柴维尔、埃尔多雷特、象牙海岸城市、科纳克里、卡萨布兰卡、阿尔及尔的韦莱斯、苏塞和埃尔多雷特）和湿疹（布拉柴维尔、埃尔多雷特、亚的斯亚贝巴、象牙海岸城市、科纳克里、马拉喀什和卡萨布兰卡）的症状流行率很高。
Phase I of the International Study of Asthma and Allergies in Childhood has provided valuable information regarding international prevalence patterns and potential risk factors in the development of asthma, allergic rhinoconjunctivitis and eczema. However, in Phase I, only six African countries were involved (Algeria, Tunisia, Morocco, Kenya, South Africa and Ethiopia). Phase III, conducted 5-6 years later, enrolled 22 centres in 16 countries including the majority of the centres involved in Phase I and new centres in Morocco, Tunisia, Democratic Republic of Congo, Togo, Sudan, Cameroon, Gabon, Reunion Island and South Africa. There were considerable variations between the various centres of Africa in the prevalence of the main symptoms of the three conditions: wheeze (4.0-21.5%), allergic rhinoconjunctivitis (7.2-27.3%) and eczema (4.7-23.0%). There was a large variation both between countries and between centres in the same country. Several centres, including Cape Town (20.3%), Polokwane (18.0%), Reunion Island (21.5%), Brazzaville (19.9%), Nairobi (18.0%), Urban Ivory Coast (19.3%) and Conakry (18.6%) showed relatively high asthma symptom prevalences, similar to those in western Europe. There were also a number of centres showing high symptom prevalences for allergic rhinoconjunctivitis (Cape Town, Reunion Island, Brazzaville, Eldoret, Urban Ivory Coast, Conakry, Casablanca, Wilays of Algiers, Sousse and Eldoret) and eczema (Brazzaville, Eldoret, Addis Ababa, Urban Ivory Coast, Conakry, Marrakech and Casablanca).