Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members
Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members
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DOI：
10.1016/j.pan.2020.04.021
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发表时间：
2020-06-01
期刊：
影响因子：
3.6
通讯作者：
Gluud, Lise Lotte
中科院分区：
文献类型：
--
作者：
Hadi, Amer;Werge, Mikkel;Gluud, Lise Lotte
背景/目的：腹痛是2019年冠状病毒病相关的已知症状之一。关于严重急性呼吸综合征冠状病毒2型感染并发急性胰腺炎的发展知之甚少。本病例报告描述了三名严重COVID-19感染的家庭成员中的两名急性胰腺炎的表现。方法：数据收集自2020年3月因COVID-19入住重症监护室的三名家庭成员。本研究由当地数据和伦理委员会（31-1521-253）审查和批准。结果：3名家庭成员中有2人被诊断为SARS-CoV-2相关急性胰腺炎。两例患者均排除了急性胰腺炎的其他原因（包括酒精、胆道梗阻/胆结石、药物、创伤、高血糖、高钙血症和低血压）。结论：这些病例突出了急性胰腺炎作为COVID-19相关并发症的重要性，并强调了测量COVID-19和腹痛患者胰腺特异性血浆淀粉酶的重要性。(C)2020年IAP和EPC。Elsevier B. V.出版，保留所有权利。
Background/Objectives: Abdominal pain is one of the known symptoms associated with coronavirus disease 2019. Little is known about the development of acute pancreatitis as a complication of severe acute respiratory syndrome coronavirus 2 infection. This case report describes the presentation of acute pancreatitis in two of three family members with severe COVID-19 infection.Methods: Data were collected from three family members admitted with COVID-19 to the intensive care unit in March 2020. This study was reviewed and approved by the local data and ethics committee (31-1521-253).Results: Two of the three family members were diagnosed with acute pancreatitis associated with SARS-CoV-2. Other causes of acute pancreatitis were excluded for both patients (including alcohol, biliary obstruction/gall stones, drugs, trauma, hypertriglyceridemia, hypercalcemia, and hypotension).Conclusions: These cases highlight acute pancreatitis as a complication associated with COVID-19 and underlines the importance of measuring pancreas-specific plasma amylase in patients with COVID-19 and abdominal pain. (C) 2020 IAP and EPC. Published by Elsevier B.V. All rights reserved.