THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors.
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors.
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DOI：
10.1111/bph.13876
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发表时间：
2017-12
影响因子：
7.3
通讯作者：
CGTP Collaborators
中科院分区：
文献类型：
--
作者：
Alexander SP;Fabbro D;Kelly E;Marrion NV;Peters JA;Faccenda E;Harding SD;Pawson AJ;Sharman JL;Southan C;Davies JA;CGTP Collaborators
简明药理学指南2017/18提供了近1800种人类药物靶标的关键特性的简明概述，重点是选择性药理学（如可用），以及药物靶标及其配体的开放获取知识库（www.guidetopharmacology.org）的链接，该知识库提供了靶标和配体特性的更详细视图。虽然《简明指南》约有400页，但与网站上提供的信息和链接相比，所提供的材料大大减少。它提供了一个永久的、可引用的、时间点的记录，可以在数据库更新后继续存在。本节的全部内容可以在http://onlinelibrary.wiley.com/doi/10.1111/bph.13876/full上找到。催化受体是指南中划分的八个主要药理学靶点之一，其他是：G蛋白偶联受体，配体门控离子通道，电压门控离子通道，其他离子通道，核激素受体，酶和转运蛋白。这些都提出了命名指南和最佳药理学工具的摘要信息，以及进一步阅读的关键参考和建议。简明指南的横向格式旨在便于比较从当代材料到2017年年中的相关目标，并取代2015/16和2013/14简明指南以及之前的受体和渠道指南中的数据。它是与基础和临床药理学联合会命名委员会（NC-IUPHAR）密切合作产生的，因此，在适当的情况下，为人类药物靶点提供官方IUPHAR分类和命名。
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13876/full. Catalytic receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
影响因子：
2.7
作者：
Hanson, GJ;Vuletich, JL;Zacheis, ML
通讯作者：
Zacheis, ML
影响因子：
15
作者：
Tilley, JW;Chen, L;Ju, G
通讯作者：
Ju, G