Relationship of blood pressure control to adherence with anti hypertensive monotherapy in 13 managed care organizations
Relationship of blood pressure control to adherence with anti hypertensive monotherapy in 13 managed care organizations
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DOI：
10.18553/jmcp.2006.12.3.239
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发表时间：
2006-04-01
影响因子：
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通讯作者：
Frech-Tamas, F
中科院分区：
文献类型：
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作者：
Bramley, TJ;Gerbino, PP;Frech-Tamas, F
目的：本研究旨在评估13个管理性医疗机构的原发性高血压（HTN）患者在血压测量前接受至少3次抗高血压药物单药治疗的患者的服药依从性与血压控制之间的关系。这是一项对13个美国健康计划在4年期间（1999-2002）的医疗和药房索赔的回顾性审查。由经过培训的卫生专业人员根据健康计划雇主数据和信息集（HEDIS）技术规范从随机选择的专利病历中收集数据。选择符合以下条件的患者：（1）在测量血压期间接受过单药治疗或固定剂量联合治疗（以一片或一粒胶囊给药）（因此排除了未接受血压药物治疗的患者）;（2）在测量血压之前接受过3次或3次以上的抗高血压药物治疗的抗高血压药物索赔;（3）在测量血压之后接受过1次或多次抗高血压药物索赔。血压的控制是根据国家联合委员会关于高血压预防、检测、评估和治疗的第六次报告（JNC 6）的指南定义的。
OBJECTIVE: This study was conducted to evaluate the relationship between medication compliance and blood pressure (BP) control among members of 13 managed care organizations with essential hypertension (HTN) who received anti hypertensive monotherapy for at least 3 pharmacy claims prior to the blood pressure measurement.METHODS: This was a retrospective review of medical and pharmacy claims over a 4-year period (1999-2002) from 13 U.S. health plans. Data were collected by trained health professionals from randomly selected patent medical records per Health Plan Employer Data and Information Set (HEDIS) technical specifications. Patients were selected if they (1) had received monotherapy or fixed-dose combination therapy (administered in one tablet or capsule) during the time BP was measured (thus those with no BP drug therapy were excluded); (2) had received 3 or more antihypertensive pharmacy claims for the anti hypertensive drug therapy prior to BP measurement; and (3) had one or more antihypertensive pharmacy claims after BP was measured. Control of BP was defined according to guidelines of the Sixth Report of the Joint National Committee (JNC 6) on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (