Ni-NHC-Catalyzed Cross-Coupling of 2-Methylsulfanylbenzofurans with Alkyl Grignard Reagents
Ni-NHC-Catalyzed Cross-Coupling of 2-Methylsulfanylbenzofurans with Alkyl Grignard Reagents
复制标题
Ni-NHC 催化 2-甲基硫基苯并呋喃与烷基格氏试剂的交叉偶联
DOI：
10.1055/s-0034-1378914
复制
发表时间：
2015
期刊：
影响因子：
2
通讯作者：
and A. Osuka
中科院分区：
文献类型：
--
作者：
A. Baralle;S. Otsuka;V. Guerin;K. Murakami;H. Yorimitsu;and A. Osuka
NiCl2(PPh3)(IPr) catalyzes cross-coupling reactions of 2-methylsulfanylbenzofurans with alkyl Grignard reagents. Other nickel complexes such as NiCl2(dppe) failed to catalyze the same reaction. The alkylation is applicable to the synthesis of a couple of protein tyrosine phosphatase inhibitors, 3-(4-biphenylyl)-2-alkylbenzofurans.
