HORMESIS - THE STIMULATION OF GROWTH BY LOW-LEVELS OF INHIBITORS
HORMESIS - THE STIMULATION OF GROWTH BY LOW-LEVELS OF INHIBITORS
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DOI：
10.1016/0048-9697(82)90066-3
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发表时间：
1982-01-01
影响因子：
9.8
通讯作者：
STEBBING, ARD
中科院分区：
文献类型：
--
作者：
STEBBING, ARD
激效是指低水平的潜在有毒物质引起的刺激作用。当这种现象第一次被发现时，它被称为阿恩特-舒尔茨定律或Hueppe规则，因为它被认为是普遍存在的。尽管这种概括在今天不被接受，但它的支持证据从未如此之多，有理由重新审视这一现象。文献证据表明，暴露于各种物质后，不仅在一系列类群中观察到生长激效，而且剂量-反应数据具有一致的形式。虽然有许多单独的假设来解释激效的具体实例，但证据表明，不同的例子可能有一个共同的解释。人们考虑了建立一般理论的可能性。
Hormesis in the name given to the stimulatory effects caused by low levels of potentially toxic agents. When this phenomenon was first identified it was called the Arndt-Schulz Law or Hueppe''s Rule, because it was thought to occur generally. Although this generalization is not accepted today, there has never been more evidence in its support, justifying a re-examination of the phenomenon. Evidence from the literature showed that not only has growth hormesis been observed in a range of taxa after exposure to a variety of agents but also that the dose-response data had a consistent form. While there were a number of separate hypothesis to explain specific instances of hormesis, the evidence suggested that different examples might have a common explanation. The possibility of a general theory was considered.