Importance of n-3 fatty acids in health and disease

Importance of n-3 fatty acids in health and disease
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DOI:
10.1093/ajcn/71.1.171s
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发表时间:
2000-01-01
影响因子:
7.1
通讯作者:
Connor, WE
Connor, WE
中科院分区:
医学1区
文献类型:
--
作者:
Connor, WE

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在过去的20年里,关于膳食n-3脂肪酸的观点已经从对其功能的猜测转变为确凿的证据,即它们不仅是必需的营养素,而且还可以有利地调节许多疾病。二十二碳六烯酸(22:6 n-3)是细胞膜磷脂的重要组成部分,特别是在大脑和视网膜中,是它们正常运作所必需的。n-3脂肪酸有利地影响动脉粥样硬化、冠心病、炎症性疾病,甚至可能是行为障碍。本增刊中的38篇文章记录了n-3脂肪酸在健康和疾病中的重要性。
In the past 2 decades, views about dietary n-3 fatty acids have moved from speculation about their functions to solid evidence that they are not only essential nutrients but also may favorably modulate many diseases. Docosahexaenoic acid (22:6n-3), which is a vital component of the phospholipids of cellular membranes, especially in the brain and retina, is necessary for their proper functioning, n-3 Fatty acids favorably affect atherosclerosis, coronary heart disease, inflammatory disease, and perhaps even behavioral disorders. The 38 articles in this supplement document the importance of n-3 fatty acids in both health and disease.