Major role for sensory feedback in soleus EMG activity in the stance phase of walking in man
Major role for sensory feedback in soleus EMG activity in the stance phase of walking in man
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DOI：
10.1111/j.1469-7793.2000.00817.x
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发表时间：
2000-03-15
影响因子：
5.5
通讯作者：
Nielsen, JB
中科院分区：
文献类型：
--
作者：
Sinkjær, T;Andersen, JB;Nielsen, JB
1.感觉反馈在猫脊髓神经运动回路的调节中起着重要作用。本研究探讨是否感觉反馈也发挥了重要作用，在步行过程中20名健康人受试者，通过停止或卸载踝关节伸肌6度为210 ms的步态站立相。在步行的站立期，踝伸肌的卸载显著（P < 0.05）减少了50%的比目鱼肌活动在早期和中期的平均起始潜伏期为64 ms。当通过局部注射利多卡因（n = 3）可逆地阻断神经支配踝背屈肌的腓总神经时，卸载产生的比目鱼肌活动下降的开始和幅度没有变化。这表明该效应不是由外周介导的拮抗神经传入的相互抑制引起的.当通过对放置在大腿周围的袖带充气而在腿部引起缺血时，由卸载产生的比目鱼肌活动减少的开始和幅度也不变。同时，Ia组介导的短潜伏期牵张反射完全消失。这表明Ia类传入神经可能与卸载引起的比目鱼肌活动减少无关。研究结果表明，来自踝伸肌的传入反馈对于这些肌肉在人类行走的站立阶段的激活具有重要意义。组II和/或组Ib的传入建议，构成这种感觉反馈的重要组成部分。
1. Sensory feedback plays a major role in the regulation of the spinal neural locomotor circuitry in cats. The present study investigated whether sensory feedback also plays an important role during walking in 20 healthy human subjects, by arresting or unloading the ankle extensors 6 deg for 210 ms in the stance phase of gait.2. During the stance phase of walking, unloading of the ankle extensors significantly (P < 0.05) reduced the soleus activity by 50% in early and mid-stance at an average onset latency of 64 ms.3. The onset and amplitude of the decrease in soleus activity produced by the unloading mere unchanged when the common peroneal nerve, which innervates the ankle dorsiflexors, was reversibly blocked by local injection of lidocaine (n = 3). This demonstrated that the effect could not be caused by a peripherally mediated reciprocal inhibition from afferents in the antagonist nerves.4. The onset and amplitude of the decrease in soleus activity produced by the unloading were also unchanged when ischaemia was induced in the leg by inflating a cuff placed around the thigh. At the same time, the group Ia-mediated short latency stretch reflex was completely abolished. This demonstrated that group Ia afferents were probably not responsible for the decrease of soleus activity produced by the unloading.5. The findings demonstrate that afferent feedback from ankle extensors is of significant importance for the activation of these muscles in the stance phase of human walking. Group II and/or group Ib afferents are suggested to constitute an important part of this sensory feedback.