Pre-erythrocytic Stage in Mammalian Malaria Parasites

Pre-erythrocytic Stage in Mammalian Malaria Parasites
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哺乳动物疟疾寄生虫的前红细胞阶段

DOI:
10.1038/161175a0
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发表时间:
1948
期刊:
影响因子:
64.8
通讯作者:
F. Hawking
F. Hawking
中科院分区:
综合性期刊1区
文献类型:
--
作者:
F. Hawking

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肖特和加纳姆曾宣布,在两只猴子的肝脏中,分别在接种食蟹猴疟原虫的子孢子后6天和7天,发现了疟原虫团。这些疟原虫团显然形成了哺乳动物疟原虫的长期寻找的红细胞前阶段,预计人类疟原虫在感染的潜伏期将显示出类似的发育变化。肖特教授非常友好地向我展示了他的准备工作,我写信来证实他的发现,在我自己的实验室里发现了类似的寄生虫。
Shortt and Garnham have announced [Nature, January 24, p. 126] the discovery of plasmodial masses in the livers of two monkeys six and seven days respectively after inoculation with sporozoites of Plasmodium cynomolgi. These plasmodial masses apparently form the long-sought pre-erythrocytic stage of mammalian malaria parasites, and it is to be expected that human malaria parasites will show similar developmental changes in the incubation period of an infection. Prof. Shortt has very kindly shown me his preparations, and I write to confirm his discovery by the finding of similar parasites in my own laboratory.