PROGRESSION OF EARLY GLAUCOMATOUS VISUAL-FIELD LOSS AS DETECTED BY BLUE-ON-YELLOW AND STANDARD WHITE-ON-WHITE AUTOMATED PERIMETRY
PROGRESSION OF EARLY GLAUCOMATOUS VISUAL-FIELD LOSS AS DETECTED BY BLUE-ON-YELLOW AND STANDARD WHITE-ON-WHITE AUTOMATED PERIMETRY
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DOI：
10.1001/archopht.1993.01090050085035
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发表时间：
1993-05-01
影响因子：
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通讯作者：
BRANDT, JD
中科院分区：
文献类型：
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作者：
JOHNSON, CA;ADAMS, AJ;BRANDT, JD
客观。-确定蓝黄视野检查是否在标准白白色视野检查明显之前显示昏迷性损害的进展。改进Humphrey视野分析仪（Humphrey Instruments，圣莱安德罗，加利福尼亚州）以进行蓝黄视野检查，从而分离和测量短波长敏感机制的灵敏度。参与者每年接受标准白对白白色自动视野检查和蓝对黄自动视野检查，持续5年。16例单眼或双眼早期青光眼视野丧失患者和62例年龄匹配的正常对照者。在基线时，32只眼睛中有25只（78.1%）表现出较大的蓝黄视野缺损，5只。(15.6 2例（6.3%）在两种检查中损失相等，2例（6.3%）在标准白对白白色视野检查中损失较大。其中7只眼（21.9%）在5年内通过标准白对白色视野检查显示出进行性视野丧失的证据，而其他25只眼（78.1%）相对稳定。在稳定组中，蓝黄视野检查的缺陷是白白色视野检查缺陷的两倍，在进行性视野丧失组中是白视野检查缺陷的三到四倍。蓝黄视野检查可有效预测早期青光眼视野缺损患者最有可能发生进行性视野缺损。蓝-黄视野检查的进行性丢失率大于标准白-白色视野检查。
Objective.-To determine whether blue-on-yellow perimetry reveals progression of glaucomatous damage before it is evident with standard white-on-white perimetry.Design.-A Humphrey field analyzer (Humphrey Instruments, San Leandro, Calif) was modified to perform blue-on-yellow perimetry to isolate and measure the sensitivity of short wavelength-sensitive mechanisms. Participants were tested annually with standard white-on-white automated perimetry and blue-on-yellow automated perimetry for 5 years.Patients.-Sixteen patients with early glaucomatous visual field loss in one or both eyes and 62 age-matched normal control subjects.Results.-At baseline, 25 (78.1%) of the 32 eyes exhibited larger deficits with blue-on-yellow perimetry, five. (15.6%) had equivalent loss with both tests, and two (6.3%) had larger deficits with standard white-on-white perimetry. Seven (21.9%) of the 32 eyes demonstrated evidence of progressive visual field loss with standard white-on-white perimetry in 5 years, while the other 25 eyes (78.1%) were relatively stable. Deficits with blue-on-yellow perimetry were twice as large as deficits with white-on-white perimetry in the stable group and were three to four times as large in the group with progressive field loss.Conclusions.-Blue-on-yellow perimetry is effective in predicting which patients with early glaucomatous visual field loss are most likely to have progressive loss. The rate of progressive loss is greater with blue-on-yellow perimetry than with standard white-on-white perimetry.