Effectiveness of education and an antibiotic-control program in a tertiary care hospital in Thailand
Effectiveness of education and an antibiotic-control program in a tertiary care hospital in Thailand
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DOI：
10.1086/500325
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发表时间：
2006-03-15
影响因子：
11.8
通讯作者：
Fraser, VJ
中科院分区：
文献类型：
--
作者：
Apisarnthanarak, A;Danchaivijitr, S;Fraser, VJ
背景我们进行了一项研究，以评估教育和抗生素控制计划的影响，抗生素处方的做法，抗生素的消费，抗菌药物耐药性和抗生素的成本在泰国的三级保健医院。对干预前一年和干预后一年进行了研究。前瞻性观察住院患者抗生素处方。人口统计学特征、医院单元、抗生素处方适应症、抗生素使用的适当性、抗生素使用不当的原因、抗生素消耗（即，抗生素使用率）、细菌耐药性和抗生素成本数据。干预措施包括教育、介绍抗生素处方表、使用抗生素处方表和处方控制。干预后，抗生素处方率下降了24%（640对400处方/1000入院; P
Background. We conducted a study to evaluate the impact of education and an antibiotic-control program on antibiotic-prescribing practices, antibiotic consumption, antimicrobial resistance, and cost of antibiotics in a tertiary care hospital in Thailand.Methods. A study of the year before and the year after the intervention was performed. Inpatient antibiotic prescriptions were prospectively observed. Demographic characteristics, hospital unit, indication for antibiotic prescription, appropriateness of antibiotic use, reasons for inappropriate antibiotic use, antibiotic consumption (i.e., the rate of antibiotic use), bacterial resistance, and antibiotic cost data were collected. Interventions included education, introduction of an antibiogram, use of antibiotic prescription forms, and prescribing controls.Results. After the intervention, there was a 24% reduction in the rate of antibiotic prescription (640 vs. 400 prescriptions/1000 admissions; P