3D Modelling and Visualisation of Heterogeneous Cell Membranes in Blender
3D Modelling and Visualisation of Heterogeneous Cell Membranes in Blender
复制标题
Blender 中异质细胞膜的 3D 建模和可视化
DOI：
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
B. Sommer
中科院分区：
文献类型：
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作者：
Mehmood Ghaffar;Niklas Biere;Daniel Jäger;Karsten Klein;F. Schreiber;O. Kruse;B. Sommer
莱茵衣藻细胞十多年来一直是研究的焦点，特别是由于其用作能源生产的替代来源。然而，这些细胞中的分子过程仍然不完全清楚，3D可视化可能有助于理解这些复杂的相互作用和过程。在以前的工作中，我们提出了立体3D（S3D）可视化的一个完整的莱茵衣藻细胞创建的3D建模框架搅拌机。这个动画已经包含了一个场景，展示了类囊体膜的说明性膜模型。在与领域专家的讨论中，发现了几个详细分析问题的可视化的缺点，并决定对其进行重新定义。开发了一种基于膜填充算法的新建模和可视化管道，可以通过用户界面进行配置，从而使用已发布的材料进行膜的组成。进行了一项专家用户研究来评估这种新方法，一半的参与者具有生物学背景，另一半具有信息学背景。在S3D反投影系统上，对新、旧两种衣原体类囊体膜模型进行了比较。评估结果表明，大多数参与者更喜欢新的，更逼真的膜可视化。然而，意见因专业知识而异，为未来的可视化提供了有价值的结论。有趣的是，分子结构的S3D呈现导致了对S3D技术的看法的积极变化。
Chlamydomonas reinhardtii cells have been in the focus of research for more than a decade, in particular due to its use as alternative source for energy production. However, the molecular processes in these cells are still not completely known, and 3D visualisations may help to understand these complex interactions and processes. In previous work, we presented the stereoscopic 3D (S3D) visualisation of a complete Chlamydomonas reinhardtii cell created with the 3D modelling framework Blender. This animation contained already a scene showing an illustrative membrane model of the thylakoid membrane. During discussion with domain experts, shortcomings of the visualisation for several detailed analysis questions have been identified and it was decided to redefine it. A new modelling and visualisation pipeline based on a Membrane Packing Algorithm was developed, which can be configured via a user interface, enabling the composition of membranes employing published material. An expert user study was conducted to evaluate this new approach, with half the participants having a biology and the other half having an informatics background. The new and old Chlamydomonas thylakoid membrane models were presented on a S3D back projection system. The evaluation results reveal that the majority of participants preferred the new, more realistic membrane visualisation. However, the opinion varied with the expertise, leading to valuable conclusions for future visualisations. Interestingly, the S3D presentation of molecular structures lead to a positive change in opinion regarding S3D technology.
DOI：
10.1109/tvcg.2014.2350479
发表时间：
2015-02-01
影响因子：
5.2
作者：
Grottel, Sebastian;Krone, Michael;Ertl, Thomas
通讯作者：
Ertl, Thomas