Pineal function: impact of microarray analysis.
Pineal function: impact of microarray analysis.
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DOI:
10.1016/j.mce.2009.07.010
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发表时间:
2010-01-27
影响因子:
4.1
通讯作者:
Coon SL
中科院分区:
文献类型:
--
作者:
Klein DC;Bailey MJ;Carter DA;Kim JS;Shi Q;Ho AK;Chik CL;Gaildrat P;Morin F;Ganguly S;Rath MF;Møller M;Sugden D;Rangel ZG;Munson PJ;Weller JL;Coon SL
Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-hour schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.
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