Severe encephalomyelitis in an immunocompetent adult with chromosomally integrated human herpesvirus 6 and clinical response to treatment with foscarnet plus ganciclovir.

Severe encephalomyelitis in an immunocompetent adult with chromosomally integrated human herpesvirus 6 and clinical response to treatment with foscarnet plus ganciclovir.
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免疫功能正常成人携带染色体整合型人类疱疹病毒 6 的严重脑脊髓炎以及对膦甲酸加更昔洛韦治疗的临床反应。

DOI:
10.1086/593315
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发表时间:
2008
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
J. Montoya
J. Montoya
中科院分区:
--
文献类型:
--
作者:
S. Troy;B. Blackburn;K. Yeom;A. F. Caulfield;M. Bhangoo;J. Montoya

文献摘要

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人类疱疹病毒6很少被确定为免疫功能正常的成人脑炎的原因。我们描述了一个病人谁有严重的脑脊髓炎,hypoglycorrhachia,和人类疱疹病毒6确定在他的脑脊液和血清,谁与膦甲酸和更昔洛韦治疗后恢复。免疫功能正常的脑炎患者应考虑人类疱疹病毒6型。
Human herpesvirus 6 has rarely been identified as a cause of encephalitis in immunocompetent adults. We describe a patient who had severe encephalomyelitis, hypoglycorrhachia, and human herpesvirus 6 identified in his cerebrospinal fluid and serum and who recovered after treatment with foscarnet and ganciclovir. Human herpesvirus 6 should be considered in immunocompetent patients with encephalitis.