Prognostic power of left atrial strain in patients with acute heart failure

Prognostic power of left atrial strain in patients with acute heart failure
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DOI:
10.1093/ehjci/jeaa013
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发表时间:
2021-02-01
影响因子:
6.2
通讯作者:
Cho, Goo-Yeong
Cho, Goo-Yeong
中科院分区:
医学1区
文献类型:
--
作者:
Park, Jae-Hyeong;Hwang, In-Chang;Cho, Goo-Yeong

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左房功能障碍可能与左室功能障碍有关,但其在急性心力衰竭(AHF)患者中的临床意义尚未得到充分研究。我们根据心力衰竭(HF)表型和房颤(AF)评估了左心房峰值心房纵向应变(帕尔斯)的预后能力。方法和结果从4312例AHF登记,我们分析了3818例患者的帕尔斯。将患者分为帕尔斯三分位数。我们还根据HF表型[HF伴射血分数降低(HFrEF)、HF伴中等射血分数(HFmrEF)或HF伴射血分数保留(HFpEF)]和AF的存在对患者进行了分类。主要结局为全因死亡率和HF住院治疗。帕尔斯与左心房容积指数呈弱相关(r=-0.310,P
Aims Left atrial (LA) dysfunction can be associated with left ventricular (LV) disorders; however, its clinical significance has not been well-studied in patients with acute heart failure (AHF). We evaluated prognostic power of peak atrial longitudinal strain (PALS) of the left atrium according to heart failure (HF) phenotypes and atrial fibrillation (AF).Methods and results From an AHF registry with 4312 patients, we analysed PALS in 3818 patients. Patients were categorized into PALS tertiles. We also divided the patients according to HF phenotypes [HF with reduced ejection fraction (HFrEF), HF with mid-range ejection fraction (HFmrEF), or HF with preserved ejection fraction (HFpEF)] and presence of AF. The primary outcomes were all-cause mortality and HF hospitalization. PALS was weakly but significantly correlated with LA volume index (r=-0.310, P