Chronic anemia, wound healing, and red cell 2,3-diphosphoglycerate.
Chronic anemia, wound healing, and red cell 2,3-diphosphoglycerate.
复制标题
慢性贫血、伤口愈合和红细胞 2,3-二磷酸甘油酸。
作者：
T. Fong;S. Ko;M. Streczyn;M. Westerman
本实验观察了家兔不同类型慢性贫血、创面愈合与红细胞2，3-二磷酸甘油酸（2，3-DPG）的关系。伤口抗张强度和能量吸收不受慢性缺铁性贫血、静脉注水引起的慢性溶血性贫血、静脉注水引起的慢性溶血性贫血和慢性苯肼诱导的贫血的影响。缺铁性贫血时红细胞2，3-DPG水平升高，慢性苯肼性贫血兔切创时红细胞2，3-DPG水平正常，注射苯肼后红细胞2，3-DPG水平降低。结果表明，慢性贫血本身不影响伤口愈合的拉伸强度和能量吸收。研究结果表明，伤口愈合过程可能与某些类型的贫血不同。
Relationships between various types of chronic anemia, wound healing, and red cell 2,3-diphosphoglycerate (2,3 DPG) were examined in rabbits. Wound tensile strength and energy absorption were not affected by chronic iron-deficiency anemia, the chronic hemolytic anemia caused by intravenous water infusion nor by chronic hemolytic anemia caused by intravenous water infusion nor by chronic phenylhydrazine-induced anemia. Red cell 2,3 DPG levels were increased in the anemia of iron deficiency and were normal in the rabbits with chronic phenylhydrazine-induced anemia at the time of wound excision but were low following phynylhydrazine injection. The results show that chronic anemia per se does not affect the tensile strength and energy adsorption of wound healing. The findings suggest that the wound healing process may differ in certain types of anemia.