Corpus callosum size in children with developmental language disorder
Corpus callosum size in children with developmental language disorder
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DOI：
10.1016/s0926-6410(00)00020-3
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发表时间：
2000-09-01
期刊：
影响因子：
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通讯作者：
Jäncke, L
中科院分区：
文献类型：
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作者：
Preis, S;Steinmetz, H;Jäncke, L
使用高分辨率在体内的胼胝体（CC）和四个胼胝体亚区的正中矢状面在21名儿童发育性语言障碍（DLD）的语音句法类型的磁共振形态测量，我们发现没有显着的解剖学差异相比，年龄和性别匹配的正常对照组。当通过将CC测量值与前脑体积相关联来解释DLD儿童中前脑体积减小7%时，也没有显著的组间差异。只有一个倾向于更大的前部和中部CC有关前脑体积被发现在DLD儿童。在我们的DLD儿童中，我们发现CC正中矢状面大小和前脑体积之间的关系与最近报道的正常成人相同，即CC面积增加到前脑体积的三分之二次方。(C)2000 Elsevier Science B.V.保留所有权利。
Using high-resolution in-vivo magnetic resonance morphometry of the midsagittal area of the corpus callosum (CC) and four callosal subareas in 21 children with developmental language disorder (DLD) of the phonologic-syntactic type we found no significant anatomical differences in comparison to an age- and gender-matched normal control group. There was also no significant between-group difference when the similar to 7% smaller forebrain volume among children with DLD was accounted for by relating CC measures to forebrain volume. Only a tendency towards a larger anterior and middle CC in relation to forebrain volume was found in DLD children. In our DLD children we found the same relationship between CC midsagittal size and forebrain volume as recently reported for normal adults, namely, that the CC area increases to the two-third power of forebrain volume. (C) 2000 Elsevier Science B.V. All rights reserved.