Intrathoracic extramedullary haematopoiesis complicated by massive haemothorax in alpha-thalassaemia
Intrathoracic extramedullary haematopoiesis complicated by massive haemothorax in alpha-thalassaemia
复制标题
α-地中海贫血胸内髓外造血并发大量血胸
作者：
Kuo;R. Lai;Chien;Jau;Huang;Hung
Intrathoracic extramedullary haematopoiesis (EMH) is a rare entity that is usually asymptomatic. A 44 year old man with alpha-thalassaemia is described who developed dyspnoea and massive left sided haemothorax. The haemoglobin disorder was established by Hgb H staining and haemoglobin electrophoretic studies. The DNA analysis revealed it to be a case of double heterozygous terminal codon mutation with the genotype ααCS/ααT. Computed tomographic scanning and magnetic resonance imaging of the thorax showed multiple paravertebral masses which were found by thoracoscopic biopsy to be extramedullary haematopoiesis. Although no additional sclerosing pleurodesis or low dose radiation therapy was given, the lung expanded well and there has been no recurrence of haemothorax to date.
影响因子：
20.3
作者：
S. L. Schrier;A. Bunyaratvej;A. Khuhapinant;S. Fucharoen;M. Aljurf;LM Snyder;C. Keifer;Lisa Ma;Narla Mohandas
通讯作者：
S. L. Schrier;A. Bunyaratvej;A. Khuhapinant;S. Fucharoen;M. Aljurf;LM Snyder;C. Keifer;Lisa Ma;Narla Mohandas
最大呼气流量和峰值呼气流量测量值的个体变化的意义。
影响因子：
9.6
作者：
Lebowitz,MD;Knudson,RJ;Robertson,G;Burrows,B
通讯作者：
Burrows,B