Effect of microchannel structure on droplet size during crossflow microchannel emulsification
Effect of microchannel structure on droplet size during crossflow microchannel emulsification
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DOI：
10.1007/s11743-000-0132-1
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发表时间：
2000-07-01
影响因子：
1.6
通讯作者：
Yonemoto, T
中科院分区：
文献类型：
--
作者：
Kawakatsu, T;Trägårdh, G;Yonemoto, T
采用交叉流型硅微通道板连续制备单分散的水包油乳液，其中制备了连续相的液体流道，并在流道的每一侧通过光刻技术精确地在微米尺度上制备了一组规则尺寸的狭缝（微通道）。平板玻璃板紧贴在微通道板上，覆盖微通道的顶部。将油通过微通道压入0.3 wt%十二烷基硫酸钠水溶液的连续相中，生成规则尺寸的油（三油酸）液滴。通过改变微通道的横截面形状、出口形状、当量直径、台阶长度等微通道结构特征，将油滴的平均尺寸调节在11.3 ~ 28.2 μ m范围内。台阶是微通道出口形成的平坦区域。在每种情况下，液滴尺寸分布都很窄，几何标准差小于等于1.03。
A monodispersed oil-in-water emulsion was continuously produced using a crossflow-type silicon microchannel plate in which a liquid flow path for the continuous phase was made, and on each side of the wall of the path, an array of regular-sized slits (microchannels) was precisely fabricated on a micrometer scale by photolithography. A flat glass plate was tightly attached to the microchannel plate to cover the top of the microchannels. Regular-sized oil (triolein) droplets were generated by pressing the oil through the microchannels into a continuous phase of 0.3 wt% aqueous sodium lauryl sulfate. The average size of the oil droplets was regulated within a range of 11.3 to 28.2 mu m by changing the microchannel structural features such as the shape of the cross section and outlet, the equivalent diameter, and the length of the terrace, which is a flat area fabricated at the outlet of the microchannels. In every case, the droplet size distribution was narrow, and the geometric standard deviation was 1.03 or less.