Magnetic resonance measurement of coronary blood flow
Magnetic resonance measurement of coronary blood flow
复制标题
冠状动脉血流量的磁共振测量
DOI：
10.1111/j.1651-2227.2004.tb00244.x
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
C. Higgins
中科院分区：
文献类型：
--
作者：
H. Sakuma;C. Higgins
冠状动脉磁共振(MR)血流测量可以通过屏气采集或呼吸触发采集来实现。在深吸气时屏气时，磁共振测量的心输出量显著降低，但优点是屏气方法需要更少的扫描时间。冠状静脉窦的血流量反映了整体心肌血流量，因为它约占左心室(LV)心肌总血流量的96%。如果用相位对比电影磁共振成像(MRI)测量冠状静脉窦内的血流量，用电影MRI测量左室心肌质量，那么总的心肌血流量和每克心肌质量的平均冠脉血流量都可以被量化。用体积法测量的冠脉血流储备在4.2-5.0倍之间。冠状动脉血流储备的无创性磁共振测量已被证明是有用的，以确定左前降支狭窄的功能意义。MR冠脉血流速度储备判断左主干或左前降支狭窄70%以上的敏感性和特异性分别为100%和83%。MR定量冠脉总血流量和每克心肌块冠脉血流量似乎是评价冠状动脉血流动力学的理想方法，对评价冠状动脉循环内皮功能障碍可能是有用的。
Magnetic resonance (MR) flow measurement in the coronary artery can be achieved with either a breath‐hold acquisition or a respiration‐triggered acquisition. MR measurements of cardiac output are significantly depressed during breath‐holding at deep inspiration, but the advantage is that the breath‐hold method requires less scan time. Blood flow in the coronary sinus reflects the global myocardial blood flow because it represents approximately 96% of the total myocardial blood flow of the left ventricle (LV). If blood flow in the coronary sinus is measured with phase‐contrast cine magnetic resonance imaging (MRI) and LV myocardial mass is measured with cine MRI, both the total myocardial blood flow and the average coronary blood flow per gram of myocardial mass can be quantified. Coronary flow reserve with volumetric MR flow measurement is measured to be within 4.2–5.0‐fold. The noninvasive MR measurement of coronary flow reserve has been shown to be useful in identifying the functional significance of stenoses in the left anterior descending artery. The sensitivity and specificity of MR coronary flow velocity reserve for identifying stenosis of 70% or greater in the left main or left anterior descending artery were 100% and 83%, respectively. The MR quantification of total coronary blood flow and coronary blood flow per gram of myocardial mass seems to be an ideal method for evaluating coronary hemodynamics and may be useful in evaluating endothelial dysfunction of the coronary circulation.