PULMONARY-FUNCTION BETWEEN 6 AND 18 YEARS OF AGE
PULMONARY-FUNCTION BETWEEN 6 AND 18 YEARS OF AGE
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DOI：
10.1002/ppul.1950150204
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发表时间：
1993-02-01
影响因子：
3.1
通讯作者：
FERRIS, BG
中科院分区：
文献类型：
--
作者：
WANG, XB;DOCKERY, DW;FERRIS, BG
根据11，630名白色儿童和989名黑人儿童的82，462次用力肺活量（FVC）、1秒用力呼气量（FEV 1）和用力呼气流量（FVC的25%-75%）的年度测量结果，描述了6-18岁儿童的肺功能。在人种和性别亚组之间比较了每3个月龄的中位身高、FVC、FEV 1、FEV 1/FVC和FEF 25 -75%。列出了每厘米身高的FVC、FEV 1、FEV 1/FVC和FEF 25 -75%的种族和性别特异性百分位数分布（生长曲线）。对于相同的身高，男孩的肺功能值大于女孩，白人的肺功能值大于黑人。肺功能随年龄线性增加，直到青春期生长突增，女孩约10岁，男孩约12岁。在青春期，肺功能与身高的关系随年龄而变化。因此，一个单一的方程或肺功能身高生长图表本身并不能完全描述在复杂的青春期的增长。然而，种族和性别特异性的肺功能与身高的生长曲线使得显示和评估单个儿童的肺功能的重复测量变得容易。种族，性别和年龄特定的回归方程的基础上提供的高度，允许在青春期的增长，提高准确性的评价，更重要的是，在与以前的观察同一个孩子。
Pulmonary function of children, aged 6-18 years is described based on 82,462 annual measurements of forced vital capacity (FVC), forced expired volume in 1 second (FEV1), and forced expiratory flow between 25% and 75% of FVC (FEF25-75%) from 11,630 white children and 989 black children. Median height, FVC, FEV1, FEV1/FVC, and FEF25-75% for each 3 months of age are compared among race and sex subgroups. Race- and sex-specific percentile distributions of FVC, FEV1, FEV1/FVC, and FEF25-75% are presented for each centimeter of height (growth curves). For the same height, boys have greater lung function values than girls, and whites have greater ones than blacks. Lung function increases linearly with age until the adolescent growth spurt at about age 1 0 years in girls and 12 in boys. The pulmonary function vs. height relationship shifts with age during adolescence. Thus, a single equation or the pulmonary function-height growth chart alone does not completely describe growth during the complex adolescent period. Nevertheless, race- and sex-specific growth curves of pulmonary function vs. height make it easy to display and evaluate repeated measures of pulmonary function for an individual child. Race-, sex-, and age-specific regression equations based on height are provided, which permit the evaluation of growth during adolescence with improved accuracy and, more importantly, in comparison with previous observations for the same child.