Immunisation of guinea pigs and cattle against ticks
Immunisation of guinea pigs and cattle against ticks
复制标题
豚鼠和牛的蜱虫免疫
作者：
J. Allen;S. Humphreys
IXODID TICKS attach to the skin of their host and remain there for several days, engorging on blood and intermittently passing salivary secretions into the host1. Several species of Ixodid ticks transmit pathogenic microorganisms along with their saliva into the host, and tick-borne diseases are of great economic importance, particularly in cattle in subtropical and tropical areas2. The control of cattle ticks by chemical acaricides has become increasingly difficult due to the emergence of acaricide-resistant strains of ticks3. An apparently novel immunological method of tick control in guinea pigs and cattle is reported here. Hosts were immunised with antigens extracted from the gut and other internal organs of partially fed ticks. Ticks which subsequently parasitised these hosts showed significantly reduced feeding and reproductive performance. These experimental results raise the theoretical possibility of controlling some species of cattle ticks by appropriate immunisation of their hosts.
