Three New Indole Alkaloids from Trigonostemon Iii
Three New Indole Alkaloids from Trigonostemon Iii
复制标题
Trigonostemon Iii 中的三种新吲哚生物碱
DOI：
10.1021/ol100715x
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发表时间：
2010-05-21
期刊：
影响因子：
5.2
通讯作者：
Hao, Xiao-Jiang
中科院分区：
文献类型：
--
作者：
Tan, Cheng-Jian;Di, Ying-Tong;Hao, Xiao-Jiang
从胡卢巴（Trigonostemon lii Y.）T.张。1-3的结构通过光谱、计算和CD激子手性方法确定。Trigonoliimine A显示出适度的抗HIV-1活性（EC（50）= 0.95 μ g/mL，TI = 7.9）。
Three unprecedented indole alkaloids, trigonoliimines A-C (1-3) with a unique polycyclic system, were isolated from the leaves of Trigonostemon lii Y. T. Chang. The structures of 1-3 were determined by the spectroscopic, computational, and CD exciton chirality approaches. Trigonoliimine A showed modest anti-HIV-1 activity (EC(50) = 0.95 mu g/mL, TI = 7.9).