Role of PROPELLER diffusion weighted imaging and apparent diffusion coefficient in the diagnosis of sellar and parasellar lesions
Role of PROPELLER diffusion weighted imaging and apparent diffusion coefficient in the diagnosis of sellar and parasellar lesions
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DOI：
10.1016/j.ejrad.2009.03.031
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发表时间：
2010-06-01
影响因子：
3.3
通讯作者：
Yamasaki, Fumiyuki
中科院分区：
文献类型：
--
作者：
Mahmoud, Omar M.;Tominaga, Atsushi;Yamasaki, Fumiyuki
目的：评估表观扩散系数（ADC）的作用，使用周期性旋转重叠平行线增强重建（PROPELLER）扩散加权成像（DWI）在鞍区和鞍旁肿块lesions.Materials和方法之间的区别：研究方案是由我们的机构审查委员会批准。我们回顾性研究了60例鞍区和鞍旁病变的患者，他们在3-T MR成像仪上接受了PROPELLER DWI。常规MRI表现为病灶与正常白色物质的信号强度（SI）比值和增强程度。ADC值计算为最小值（ADC-MIN）、平均值（ADC-MEAN）和最大值（ADC-MAX）。所有患者均接受手术治疗，所有标本均进行组织学检查。采用T1和T2加权像的SI比值进行Logistic判别分析结果：出血性垂体腺瘤的ADC最小值（ADC-MIN）明显低于其他MRI表现相似的垂体腺瘤（非出血性垂体腺瘤、颅咽管瘤、Rathke囊肿;准确率100%）;有用的截断值为0.700 x 10（-3）mm（2）/s。脑膜瘤的ADC-MAX低于非出血性垂体腺瘤（准确率90.3%; p < 0.01）。结论：PROPELLER DWI对磁敏感伪影的敏感性低于单次激发平面回波DWI，因此在鞍区及鞍旁病变的检查中更有价值。ADC值的计算有助于区分各种鞍区和鞍旁病变。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
Objective: To evaluate the role of the apparent diffusion coefficient(ADC) using periodically rotated over-lapping parallel lines with enhanced reconstruction (PROPELLER) diffusion weighted imaging (DWI) in the differentiation between sellar and parasellar mass lesions.Materials and methods: The study protocol was approved by our institutional review board. We retrospectively studied 60 patients with sellar and parasellar lesions who had undergone PROPELLER DWI on a 3-T MR imager. Conventional MRI findings were expressed as the ratio of signal intensity (SI) in the lesions to the normal white matter and the degree of contrast enhancement. ADC values were calculated as the minimum (ADC-MIN), mean (ADC-MEAN), and maximum (ADC-MAX). All patients underwent surgery and all specimens were examined histologically. Logistic discriminant analysis was performed by using the SI ratios on T1- and T2-weighted images (T1-WI, T2-WI), the degree of enhancement, and absolute ADC values as independent variables.Results: ADC-MIN of hemorrhagic pituitary adenomas was lower than of the other lesions with similar appearance on conventional MRI (non-hemorrhagic pituitary adenomas, craniopharyngiomas, Rathke's cleft cysts; accuracy 100%); the useful cut-off value was 0.700 x 10(-3) mm(2)/s. ADC-MAX of meningiomas was lower than of non-hemorrhagic pituitary adenomas (accuracy 90.3%; p < 0.01). ADC-MIN of cranio-pharyngiomas was lower than of Rathke's cleft cysts( accuracy 100%; p < 0.05).Conclusion: As PROPELLER DWI is less sensitive to susceptibility artifacts than single-shot echoplanar DWI, it is more useful in the examination of sellar and parasellar lesions. Calculation of the ADC values helps to differentiate between various sellar and parasellar lesions. (C) 2009 Elsevier Ireland Ltd. All rights reserved.