Molecular characterization of voltage and cyclic nucleotide-gated potassium channels in kidney.
Molecular characterization of voltage and cyclic nucleotide-gated potassium channels in kidney.
复制标题
肾脏电压和环核苷酸门控钾通道的分子特征。
DOI：
10.1038/ki.1995.386
复制
发表时间：
1995
影响因子：
19.6
通讯作者：
Desir,GV
中科院分区：
文献类型：
--
作者：
Desir,GV
Potassium (K+) channels constitute a diverse group of membrane proteins that facilitate the passive movement (driven by the electrochemical gradient for K+) of K+across cell membranes. One or more type of K+channel can be detected in virtually all mammalian cells. There are extensive data on the kinetic properties and the physiology of K+channels in kidney. More recently, the initial molecular characterization of some types of renal K channels has been reported. This paper will briefly review the potential physiologic role and the molecular biology of two types of renal K channels, namely those that are regulated by voltage and those that are regulated by cyclic nucleotide.
