ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing
ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing
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DOI：
10.1021/op900305v
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发表时间：
2010-03-01
影响因子：
3.4
通讯作者：
Gaunt, Nigel L.
中科院分区：
文献类型：
--
作者：
Carter, Catherine F.;Lange, Heiko;Gaunt, Nigel L.
据报道，新开发的ReactIR流动池是一种方便和通用的在线分析工具，可用于连续的WHO化学处理。该流动池采用ATR技术，使用标准的OmniFit(高效液相色谱)连接件直接连接到反应流动流中，可与中尺度和微尺度流动化学设备结合使用。IC IR分析软件(4.0版)能够监控试剂消耗和产品形成，帮助快速优化程序。还可以在原位观察到短暂的活性中间体，从而进一步从机理上深入了解复杂的转变。
A newly developed ReactIR flow cell is reported as a convenient and versatile inline analytical tool for continuous How chemical processing. The flow cell, operated with ATR technology, is attached directly into a reaction flow stream using standard OmniFit (HPLC) connections and can be used in combination with both meso- and microscale flow chemistry equipment. The iC IR analysis software (version 4.0) enables the monitoring of reagent consumption and product formation, aiding the rapid optimisation of procedures. Short-lived reactive intermediates can also be observed in situ, giving further mechanistic insight into complex transformations.