Assessment of the arachidonic acid content in foods commonly consumed in the American diet
Assessment of the arachidonic acid content in foods commonly consumed in the American diet
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评估美国饮食中常见食物中的花生四烯酸含量
作者：
Laura M Taber;C. Chiu;J. Whelan
花生四烯酸(AA)是一种参与细胞调节的极其重要的脂肪酸。当在饮食中提供时，它被牢固地结合到膜磷脂中，并在体内和体外促进二十烷类化合物的生物合成；然而，关于食物和饮食中AA的水平存在争议。这项研究测定了牛肉(肋眼)、鸡肉(胸肉和大腿)、鸡蛋、猪肉(腰肉)、火鸡(胸肉)和金枪鱼的熟和生部分中AA的含量；并将这些结果与发表在《农业手册》第8号(HB-8)上的值进行了比较。煮熟的部分按照HB-8中所述的方法准备。除鸡腿和金枪鱼外，所分析的选定食物的AA(w/w)水平普遍显著高于HB-8公布的数值。在牛肉(生的和熟的)、火鸡胸肉(生的和熟的)和猪肉(熟的)中观察到的差异最大，它们的AA水平是HB-8的两倍。相比之下，金枪鱼中AA和n-3脂肪酸的含量几乎是HB-8的一半。目前的数据表明，HB-8倾向于低估美国人饮食中常用的一些食物中的AA含量，应考虑采取新的举措来验证和更新当前食品脂肪酸组成的数据库。
Arachidonic acid (AA) is an extremely important fatty acid involved in cell regulation. When provided in the diet, it is cogently incorporated in membrane phospholipids and enhances eicosanoid biosynthesis in vivo and in vitro; however, controversy exists as to the levels of AA in food and in the diet. This study determined the amount of AA in cooked and raw portions of beef (rib eye), chicken (breast and thigh), eggs, pork (loin), turkey (breast), and tuna; it compared these results to values published in Agriculture Handbook No. 8 (HB-8). The cooked portions were prepared as described in HB-8. With the exception of chicken thigh and tuna, the levels of AA (w/w) in the selected foods analyzed were significantly higher, in general, than those values published in HB-8. The greatest differences were observed in beef (raw and cooked), turkey breast (raw and cooked), and pork (cooked) where AA levels were twice that of the values in HB-8. In contrast, the AA and n-3 fatty acid contents in tuna were almost half the HB-8 values. The present data indicate that HB-8 tends to underreport the amounts of AA in a number of foods commonly consumed in the American diet, and new initiatives should be considered to validate and update the current database for fatty acid composition of foods.
花生四烯酸是人类热休克基因转录的有效调节剂。
DOI：
10.1073/pnas.91.6.2280
发表时间：
1994
影响因子：
11.1
作者：
Jurivich,DA;Sistonen,L;Sarge,KD;Morimoto,RI
通讯作者：
Morimoto,RI
花生四烯酸通过抑制转录和增强 mRNA 更新来下调 3T3-L1 脂肪细胞中的胰岛素依赖性葡萄糖转运蛋白基因 (GLUT4)。
DOI：
--
发表时间：
1994
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Tebbey,PW;McGowan,KM;Stephens,JM;Buttke,TM;Pekala,PH
通讯作者：
Pekala,PH