Mild organocatalytic α-methylenation of aldehydes
Mild organocatalytic α-methylenation of aldehydes
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DOI：
10.1021/jo052529q
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发表时间：
2006-03-17
影响因子：
3.6
通讯作者：
Pihko, PM
中科院分区：
文献类型：
--
作者：
Erkkilä, A;Pihko, PM
[图表]描述了一种快速且非常方便的醛与甲醛水溶液的α-亚甲基化方法。两个最佳的催化系统，允许短的反应时间，并提供良好的功能化产品的优良产率（高达99%）和化学选择性。
[GRAPHICS]A rapid and extremely convenient method for alpha-methylenation of aldehydes with aqueous formaldehyde is described. Two optimal catalytic systems are presented that allow short reaction times and afford the functionalized products in good to excellent yields (up to 99%) and chemoselectivity.