A 2-year study of liquid nitrogen therapy in cutaneous leishmaniasis
A 2-year study of liquid nitrogen therapy in cutaneous leishmaniasis
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DOI：
10.1046/j.1365-4362.1997.00045.x
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发表时间：
1997-06-01
影响因子：
3.6
通讯作者：
Hebeheba, H
中科院分区：
文献类型：
--
作者：
AlMajali, O;Routh, HB;Hebeheba, H
背景：在治疗皮肤利什曼病的不同方法中，液氮被认为是一种有效的治疗方法，副作用非常轻微。在468例皮肤利什曼病患者中，293例采用液氮治疗，其余采用其他已知的治疗方式。结果冷冻手术液氮治疗的293例患者中215例得到了适当的随访，临床反应显著有效，未发现全身不良反应。轻微的皮肤并发症很少见，包括色素减退、色素沉着和瘢痕形成。结论根据本研究的结果，液氮疗法可能被认为是一种有效的皮肤利什曼病治疗方法。
Background Among the different modalities for treatment of cutaneous leishmaniasis, liquid nitrogen is considered an effective therapy with very mild side-effects.Methods A study was conducted using liquid nitrogen topically for the treatment of cutaneous leishmaniasis in the King Hussain Medical Centre, Amman-Jordan. Among 468 patients of cutaneous leishmaniasis, 293 were treated with liquid nitrogen and the rest were treated with other known treatment modalities.Results Of the patients treated with cryo surgery liquid nitrogen, 215 of 293 permitted appropriate follow-up; the clinical response was significant and effective, No systemic adverse effects were noted. Mild cutaneous complications were infrequent, and included hypopigmentation, hyperpigmentation, and scar formation.Conclusions From the results of this study, liquid nitrogen therapy may be considered an effective treatment for cutaneous leishmaniasis.