Sudden Death from Systemic Rotavirus Infection and Detection of Nonstructural Rotavirus Proteins
Sudden Death from Systemic Rotavirus Infection and Detection of Nonstructural Rotavirus Proteins
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DOI：
10.1128/jcm.01303-11
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发表时间：
2011-12-01
影响因子：
9.4
通讯作者：
Ozaki, Nozomu
中科院分区：
文献类型：
--
作者：
Nakano, Ineko;Taniguchi, Koki;Ozaki, Nozomu
一名2.5岁女孩在患轮状病毒胃肠炎期间突然死亡。尸检显示脑病伴轮状病毒全身感染。在这里，我们提供了轮状病毒在多个器官中复制的证据。我们的研究结果表明，儿童轮状病毒感染可以通过病毒血症扩展到肠道以外。
A 2.5-year-old girl died suddenly during the course of rotavirus gastroenteritis. The autopsy showed encephalopathy with rotavirus systemic infection. Here, we provide evidence of rotavirus replication in multiple organs. Our findings clarify that rotavirus infection in children can extend beyond the intestinal tract through viremia.