Occupational allergic contact dermatitis caused by isocyanates
Occupational allergic contact dermatitis caused by isocyanates
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DOI：
10.1034/j.1600-0536.2002.470509.x
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发表时间：
2002-11-01
影响因子：
5.5
通讯作者：
Bruze, M
中科院分区：
文献类型：
--
作者：
Goossens, A;Detienne, T;Bruze, M
1978年至2001年间，我科共收治22例异氰酸酯和/或聚氨酯引起的职业性变态反应性接触性皮炎。13个对异氰酸酯呈阳性反应，其中10个还与二氨基二苯基甲烷(MDA)反应，二氨基二苯基甲烷用于生产或加工异氰酸酯和聚氨酯；9个只对MDA反应。本研究的目的是确定导致这些树脂接触性过敏的行业和行业。这类患者必须用工作中接触的异氰酸酯进行斑贴测试，并且必须考虑到丙二醛的阳性反应作为异氰酸酯敏感性的标志。
Between 1978 and 2001, 22 patients were diagnosed with occupation-related allergic contact dermatitis from isocyanates and/or polyurethanes in our clinic . 13 had a positive reaction to the isocyanates, of whom 10 also reacted to diaminodiphenylmethane (MDA), which is used in the production or processing of isocyanates and polyurethanes; 9 reacted only to MDA. The object of the present study was to identify the trades and industries responsible for the development of contact allergy to these resins. Such patients must be patch tested with the isocyanates contacted at work, and account must be taken of positive reactions to MDA as a marker for isocyanate sensitivity.