An analysis of fusion cage migration in unilateral and bilateral fixation with transforaminal lumbar interbody fusion

An analysis of fusion cage migration in unilateral and bilateral fixation with transforaminal lumbar interbody fusion
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DOI:
10.1007/s00586-012-2458-x
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发表时间:
2013-02-01
影响因子:
2.8
通讯作者:
Bailey, Richard Anthony
Bailey, Richard Anthony
中科院分区:
医学3区
文献类型:
--
作者:
Duncan, Jan William;Bailey, Richard Anthony

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研究内固定(单侧或双侧固定)是否对融合器迁移率有影响。这项经椎间孔腰椎椎体间融合术的临床研究涉及116名患者,他们被随机分配到单侧(n = 57)或双侧(n = 59)固定。失访14例(单侧组11例,双侧组3例)。单侧固定组男性20例,女性26例。单侧组平均年龄53.5岁(范围18-77岁),术前诊断为退行性椎间盘病变伴或不伴椎间盘突出(n = 44),退行性椎体滑脱伴椎管狭窄(n = 2)。双侧固定组男性20例,女性36例。双侧组患者平均年龄为55.7岁(范围26-82岁),术前诊断为伴有或不伴有椎间盘突出的退行性椎间盘疾病(n = 40)和伴有椎管狭窄的退行性椎体滑脱(n = 16)。共发现笼内迁移17例;其中,11只来自单侧组,6只来自双侧组,导致笼子迁移率分别为23%和11% (p = 0.03)。关于移徙案件,5人为男性,12人为女性。年龄27 ~ 79岁(平均55岁)。我们得出结论,在一些接受TLIF的患者中,单侧固定不够稳定,不足以防止融合器移动。
To investigate if instrumentation (unilateral vs. bilateral fixation) has an effect on the rate of fusion cage migration.This clinical study of transforaminal lumbar interbody fusion involved a prospective group of 116 patients who were randomly assigned to either unilateral (n = 57) or bilateral (n = 59) fixation. Fourteen were lost to follow-up (11 from the unilateral group and 3 from the bilateral group).The unilateral fixation group consisted of 20 male and 26 female patients. In the unilateral group, the mean age was 53.5 years (range, 18-77), and the preoperative diagnosis consisted of degenerative disc disease, with or without herniated disc (n = 44), and degenerative spondylolisthesis with spinal stenosis (n = 2). The bilateral fixation group consisted of 20 male and 36 female patients. In the bilateral group, the mean age was 55.7 years (range, 26-82), and the preoperative diagnosis consisted of degenerative disc disease, with or without herniated disc (n = 40), and degenerative spondylolisthesis with spinal stenosis (n = 16). A total of 17 cases of cage migration were found; of these, 11 were from the unilateral group and 6 from the bilateral group, resulting in rates of cage migration of 23 and 11 % (p = 0.03), respectively. In regard to migration cases, 5 were male and 12 were female. Ages ranged from 27 to 79 years (mean age, 55 years).We conclude that unilateral fixation is not stable enough to prevent fusion cage migration in some patients who undergo TLIF.