Five-Year Follow-Up of Peyronie's Graft Surgery: Outcomes and Patient Satisfaction
Five-Year Follow-Up of Peyronie's Graft Surgery: Outcomes and Patient Satisfaction
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DOI：
10.1111/j.1743-6109.2010.02102.x
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发表时间：
2011-02-01
影响因子：
3.5
通讯作者：
Brock, Gerald
中科院分区：
文献类型：
--
作者：
Chung, Eric;Clendinning, Eric;Brock, Gerald
引言：佩罗尼氏病（PD）的移植手术与显著的长期风险相关。目的：通过至少5年的随访，评价移植修复的临床和功能结局。方法：对1999年5月至2005年5月期间所有接受重建移植手术治疗PD的男性进行回顾性数据库和第三方电话调查。主要结局指标：患者人口统计学，术前进行国际勃起功能指数（IIEF-5）评分和阴茎多普勒超声检查。随访评估包括手术结果和患者总体满意度。结果：共有86例患者接受了Peyronie移植修复术，平均年龄为54.6岁（34 - 73岁）。平均随访98（61 ~ 120）个月。20例患者接受真皮移植，33例患者接受Tutoplast移植，33例患者接受Stratasis小肠粘膜下层移植。阴茎弯曲度大于60度在Tutoplast和Stratasis组中更常见。12例患者术前使用磷酸二酯酶5型抑制剂或静脉内药物。在审查时，只有46例（53%）患者能够联系并同意接受电话采访。虽然术后6个月随访显示阴茎弯曲的解决效果极佳，或明显更小，但真皮组的这一数字降至50%，Tutoplast组为87%，Stratasis组为76%。在最近的随访中，患者自我评估还报告了阴茎长度进一步缩短。糖尿病组IIEF-5评分随勃起功能障碍的发生而加重（P < 0.01）。在5点量表的总体满意度为2.6与超过65%的患者不满意的结果的佩罗尼氏移植surgery.Conclusions的阴茎弯曲，阴茎长度损失，和新发的艾德复发并不罕见的后遗症，并与一个显着的患者不满意率时，5年的随访是实现。Chung E，Clendining E，Lessard L，and Brock G. Peyronie移植手术的5年随访：结局和患者满意度。J Sex Med 2011;8：594-600.
Introduction.Graft surgery for Peyronie's disease (PD) is associated with significant long-term risks.Aim.To evaluate the clinical and functional outcomes of graft repairs with a minimum of 5-year follow-up.Methods.A retrospective review of database and third party telephone survey was undertaken in all men who underwent reconstructive graft procedures for PD between May 1999 and May 2005.Main Outcome Measures.Patient demographics, International Index of Erectile Function (IIEF-5) scores, and penile Doppler ultrasonography were performed preoperative. Follow-up assessments included surgical outcomes and overall patient satisfactions.Results.A total of 86 patients with an average age of 54.6 (34 to 73) years underwent Peyronie's graft repair. The average follow-up was 98 (61 to 120) months. Twenty patients received dermal graft whereas 33 patients underwent Tutoplast graft and 33 patients had Stratasis small intestinal submucosa graft. Penile curvature greater than 60 degrees was more common in the Tutoplast and Stratasis groups. Twelve patients used phosphodiesterase type 5 inhibitors or intracavenous agents preoperatively. At the time of review, only 46 (53%) patients were able to be contacted and consented for telephone interview. Although 6 months of postoperative follow-up showed excellent resolution, or significantly less, penile curvature, this figures decreased to 50% in dermal, 87% in Tutoplast, and 76% in Stratasis patients. Further penile length shortening was also reported on patient self-assessment at the recent follow-up. Worsening of IIEF-5 scores were noted with the development of erectile dysfunction was more pronounced in the diabetic cohort (P < 0.01). The overall satisfaction on a 5-point scale was 2.6 with more than 65% of patients dissatisfied with the outcomes of the Peyronie's graft surgery.Conclusions.The recurrence of penile curvature, penile length loss, and the new-onset of ED are not uncommon sequelae and are associated with a significant patient dissatisfaction rate when a 5-year follow-up is achieved. Chung E, Clendinning E, Lessard L, and Brock G. Five-year follow-up of Peyronie's graft surgery: Outcomes and patient satisfaction. J Sex Med 2011;8:594-600.