Association between "loco-check" and EuroQol, a comprehensive instrument for assessing health-related quality of life: a study of the Japanese general population
Association between "loco-check" and EuroQol, a comprehensive instrument for assessing health-related quality of life: a study of the Japanese general population
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DOI：
10.1007/s00776-014-0602-7
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发表时间：
2014-09-01
影响因子：
1.7
通讯作者：
Takagishi, Kenji
中科院分区：
文献类型：
--
作者：
Iizuka, Yoichi;Iizuka, Haku;Takagishi, Kenji
“火车头综合症”的概念是由日本骨科学会(JOA)于2007年提出的，指的是老年人因肌肉、骨骼和关节等运动器官功能减退而卧床不起的风险。对442名日本受试者(183名男性和259名女性)进行了基于“Loco-Check”、EuroQol-5维度(EQ-5D)和EuroQol-VAS(EQ-VAS)的LS和HRQL的评估。如果受试者对七项“机车检查”中的一项或多项回答“是”，他们就被分配到机车综合征疑似组(L组)。如果他们在所有七个项目上的回答都是否定的，他们就被分配到机车综合征非疑似组(NL组)。我们调查了通过“定位检查”获得的LS筛查结果与使用EQ-5D效用值和EQ-VAS评分确定的HRQL状态之间的关系。39.6%的受试者基于“定位检查”而怀疑LS。在单因素分析中，根据EQ-5D和EQ-VAS，L组的年龄明显高于NL组，女性与男性的比例高于NL组，HRQL的降低程度也高于NL组。Logistic回归分析显示，EQ-5D效用值和EQ-VAS评分与LS相关，差异有统计学意义。此外，研究还发现，在“LOCO-CHECK”、EQ-5D或EQ-VAS中回答“是”的项目数之间存在相关性。也就是说，在EQ-5D和EQ-VAS中得到肯定答案的条目越多，HRQQL就越低。我们证明了基于“LOO-CHECK”的LS的发现与EQ-5D效用值和EQ-VAS得分显著相关，并且通过“LOO-CHECK”被确定患有LS的人群也降低了HRQOL。此外，据推测，由于运动功能障碍导致的HRQOL降低的严重程度可以通过“定位检查”来确定。
The concept of "locomotive syndrome" (LS) was proposed by the Japanese Orthopaedic Association (JOA) in 2007 to refer to the risk of elderly individuals becoming bedridden because of reduced function of locomotive organs, for example muscles, bones, and joints. The purpose of this study was to clarify the association between LS screening results based on "loco-check" and health-related quality of life (HRQoL) assessed by use of EuroQol.Four-hundred and forty-two Japanese subjects (183 males and 259 females) were evaluated for LS and HRQoL by use of "loco-check," EuroQol-5 dimensions (EQ-5D), and EuroQol-VAS (EQ-VAS). If the subjects answered "yes" to one or more of the seven items of "loco-check," they were assigned to a locomotive syndrome suspected group (L group). If they answered "no" to all seven items, they were assigned to a locomotive syndrome not suspected group (NL group). We investigated the association between the screening LS results obtained by use of "loco-check" and HRQoL status determined by use of EQ-5D utility value and EQ-VAS score.LS was suspected among 39.6 % of the subjects on the basis of "loco-check." In univariate analysis, significantly higher age, higher female-to-male ratio, and more reduced HRQoL were observed in the L group than in the NL group, according to EQ-5D and EQ-VAS. Logistic regression analysis showed that EQ-5D utility value and EQ-VAS score were associated with LS and the difference was statistically significant. Furthermore, correlations were found between the number of items with a "yes" answer on "loco-check", EQ-5D, or EQ-VAS. That is, a larger number of items with a "yes" answer on "loco-check" was associated with reduced HRQoL assessed by use of EQ-5D and EQ-VAS.We demonstrated that a finding of LS on the basis of "loco-check" is significantly associated with EQ-5D utility value and EQ-VAS score, and that a population identified as having LS by use of "loco-check" also had reduced HRQoL. Furthermore, it is speculated that the severity of reduced HRQoL because of locomotive dysfunction can be determined by use of "loco-check".