Assessment of ultrasonographic features of polycystic ovaries is associated with modest levels of inter-observer agreement
Assessment of ultrasonographic features of polycystic ovaries is associated with modest levels of inter-observer agreement
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DOI：
10.1186/1757-2215-2-6
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发表时间：
2009-01-01
影响因子：
4
通讯作者：
Pierson, Roger A.
中科院分区：
文献类型：
--
作者：
Lujan, Marla E.;Chizen, Donna R.;Pierson, Roger A.
背景资料：多囊卵巢综合征（PCOS）是一种多囊卵巢综合征（PCOS）的常见病，也是一种多囊卵巢综合征的常见病。为了更好地了解这种变化的性质，我们提出了评估水平的观察员之间的协议时，识别和量化个人超声特征的多囊ovarias.Methods：数字记录的经阴道超声扫描进行了评估，在30名妇女与PCOS的四个观察员与培训，放射学或生殖内分泌学。观察员评估扫描结果：1）每个卵巢>= 2 mm的卵泡数量，2）最大卵泡直径，3）卵巢体积，4）卵泡分布模式和5）黄体（CL）的存在。多个评定者的Lin一致性相关系数和Kappa统计量用于评估观察者间的一致性。观察者之间的一致性范围为卵泡计数0.08 - 0.63，最大卵泡直径0.27 - 0.88，卵巢体积0.63 - 0.86，卵泡分布模式为0.51至0.76，CL存在为0.76至0.90。总体而言，生殖内分泌学家表现出更好的协议时，评价多囊卵巢的超声特征相比，放射科医生（0.71与0.53; p = 0.04）。结论：观察员间的协议评估多囊卵巢的超声特征是中等至较差。这些发现支持需要标准化的培训模块来描述超声检查中多囊卵巢的形态。
Background: There is growing acceptance that polycystic ovaries are an important marker of polycystic ovary syndrome (PCOS) despite significant variability when making the ultrasound diagnosis. To better understand the nature of this variability, we proposed to evaluate the level of inter-observer agreement when identifying and quantifying individual ultrasonographic features of polycystic ovaries.Methods: Digital recordings of transvaginal ultrasound scans performed in thirty women with PCOS were assessed by four observers with training in Radiology or Reproductive Endocrinology. Observers evaluated the scans for: 1) number of follicles >= 2 mm per ovary, 2) largest follicle diameter, 3) ovarian volume, 4) follicle distribution pattern and 5) presence of a corpus luteum (CL). Lin's concordance correlation coefficients and kappa statistics for multiple raters were used to assess inter-observer agreement.Results: Agreement between observers ranged from 0.08 to 0.63 for follicle counts, 0.27 to 0.88 for largest follicle diameter, 0.63 to 0.86 for ovarian volume, 0.51 to 0.76 for follicle distribution pattern and 0.76 to 0.90 for presence of a CL. Overall, reproductive endocrinologists demonstrated better agreement when evaluating ultrasonographic features of polycystic ovaries compared to radiologists (0.71 versus 0.53; p = 0.04).Conclusion: Inter-observer agreement for assessing ultrasonographic features of polycystic ovaries was moderate to poor. These findings support the need for standardized training modules to characterize polycystic ovarian morphology on ultrasonography.