Cognitive impairment following frontal lobe damage and its relevance to human amnesia.
Cognitive impairment following frontal lobe damage and its relevance to human amnesia.
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DOI：
10.1037//0735-7044.103.3.548
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发表时间：
1989-06
影响因子：
1.9
通讯作者：
J. Janowsky;A. Shimamura;M. Kritchevsky;L. Squire
中科院分区：
文献类型：
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作者：
J. Janowsky;A. Shimamura;M. Kritchevsky;L. Squire
额叶病变是否可以解释在科尔萨科夫综合征的健忘症患者中观察到的一些认知障碍进行了调查。各种认知和记忆测试，给予患者与局限性额叶病变，患者与Korsakoff综合征，非Korsakoff健忘症患者，和控制SS。额叶损伤的患者没有健忘症。然而，他们表现出2个缺陷，这也表现为Korsakoff综合征患者，但不包括其他健忘症患者：（a）威斯康星州卡片分类测试的损害和（B）痴呆评定量表的启动和保存子量表的损害。因此，额叶病理学可以解释在Korsakoff综合征患者中观察到的一些认知缺陷。
Whether frontal lobe pathology can account for some of the cognitive impairment observed in amnesic patients with Korsakoff's syndrome was investigated. Various cognitive and memory tests were given to patients with circumscribed frontal lobe lesions, patients with Korsakoff's syndrome, non-Korsakoff amnesic patients, and control Ss. Patients with frontal lobe lesions were not amnesic. Nevertheless they exhibited 2 deficits that were also exhibited by patients with Korsakoff's syndrome but not by other amnesic patients: (a) impairment on the Wisconsin Card Sorting Test and (b) impairment on the Initiation and Preservation subscale of the Dementia Rating Scale. Thus, frontal lobe pathology can explain some of the cognitive deficits observed in patients with Korsakoff's syndrome.