Silver nanoparticles: synthesis, properties, and therapeutic applications.
Silver nanoparticles: synthesis, properties, and therapeutic applications.
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DOI：
10.1016/j.drudis.2014.11.014
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发表时间：
2015-05
影响因子：
7.4
通讯作者：
Chen G
中科院分区：
文献类型：
--
作者：
Wei L;Lu J;Xu H;Patel A;Chen ZS;Chen G
银纳米粒子（AgNPs）由于其固有的治疗特性而被广泛应用于生物医学领域。在这里，我们介绍了合成银纳米粒子的方法，并讨论其物理化学，局部表面等离子体共振（LSPR）和毒性特性。我们还回顾了银纳米颗粒对人类健康和环境的影响，沿着的潜在机制。更重要的是，我们强调了新出现的应用AgNPs作为抗病毒剂，光敏剂和/或放射增敏剂，和抗癌治疗剂在白血病，乳腺癌，肝细胞癌，肺癌，皮肤和/或口腔癌的治疗。
Silver nanoparticles (AgNPs) have been widely used in biomedical fields because of their intrinsic therapeutic properties. Here, we introduce methods of synthesizing AgNPs and discuss their physicochemical, localized surface plasmon resonance (LSPR) and toxicity properties. We also review the impact of AgNPs on human health and the environment along with the underlying mechanisms. More importantly, we highlight the newly emerging applications of AgNPs as antiviral agents, photosensitizers and/or radiosensitizers, and anticancer therapeutic agents in the treatment of leukemia, breast cancer, hepatocellular carcinoma, lung cancer, and skin and/or oral carcinoma.