Editorial overview: Understanding membrane and membrane proteins: Where do we go now?
Editorial overview: Understanding membrane and membrane proteins: Where do we go now?
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编辑概述：了解膜和膜蛋白：我们现在该何去何从？
DOI：
10.1016/j.sbi.2022.102471
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发表时间：
2022
影响因子：
6.8
通讯作者：
Palacín,Manuel
中科院分区：
文献类型：
--
作者：
Banerjee,Anirban;Palacín,Manuel
How the complex environment of a membrane protein interplays with its structure and function is illustrated in the review by Jimenez-Munguia on interferon-induced transmembrane protein 3 (IFITM3), an antiviral protein that blocks fusion of the viral membrane with the host cell. In their review, they touch upon the possibility of IFITM3 adopting different topologies which overlays with the dependence of its activity on the local lipid composition of the membrane, thus making for an intricate mechanistic question which is yet to be understood in complete molecular detail.
