The emergence of pan-resistant Gram-negative pathogens merits a rapid global political response
The emergence of pan-resistant Gram-negative pathogens merits a rapid global political response
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DOI：
10.1093/jac/dkr378
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发表时间：
2012-01-01
影响因子：
5.2
通讯作者：
Toleman, Mark A.
中科院分区：
文献类型：
--
作者：
Walsh, Timothy R.;Toleman, Mark A.
最近媒体对新德里金属-β-内酰胺酶（NDM-1）的报道将抗生素耐药性重新置于政治地图上，如果只是出于错误的原因，主要是对NDM-1命名的反应以及医疗旅游被故意针对的错误假设。然而，关于NDM-1的工作无疑突出了新的抗生素耐药性机制通过经济全球化的快速传播。NDM-1的例子也放大了对公共资助的全球抗生素监测系统的迫切需要，而不仅仅是国家或区域系统。此外，迫切需要建立一个全球工作队，在抗生素管理和执行遏制抗生素耐药性的措施方面加强国际透明度和问责制。应建立一个国际抗生素管理指数，该指数与每个国家的国内生产总值（GDP）相关，并评估其GDP中有多少用于旨在控制抗生素耐药性的医疗卫生计划。
Recent media coverage of New Delhi metallo-beta-lactamase (NDM-1) put antibiotic resistance back on the political map if only for the wrong reasons, mainly the reaction to the naming of NDM-1 and the incorrect assumption that medical tourism was being deliberately targeted. However, work on NDM-1 has most certainly highlighted the rapid dissemination of new antibiotic resistance mechanisms via economic globalization. The example of NDM-1 has also magnified the desperate need for a publicly funded global antibiotic surveillance system rather than just national or regional systems. Furthermore, there is a pressing need to establish a global task force to enforce international transparency and accountability on antibiotic stewardship and the implementation of measures to curb antibiotic resistance. An international antibiotic stewardship index should be established that is related to each country's gross domestic product (GDP) and assesses how much of their GDP is committed to publically funded health initiatives aimed at controlling antibiotic resistance.