Complete Genome Sequence and Annotation of the Treponema pallidum subsp pallidum Chicago Strain

Complete Genome Sequence and Annotation of the Treponema pallidum subsp pallidum Chicago Strain
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DOI:
10.1128/jb.00159-10
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发表时间:
2010-05-15
影响因子:
3.2
通讯作者:
Rockey, Daniel D.
Rockey, Daniel D.
中科院分区:
生物学3区
文献类型:
--
作者:
Giacani, Lorenzo;Jeffrey, Brendan M.;Rockey, Daniel D.

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在梅毒研究中,1912年分离出的梅毒螺旋体尼科尔斯株是最广泛的研究。最近,T.出现苍白球菌株;因此,我们对芝加哥株的基因组进行了测序和注释,以促进和鼓励该株在梅毒发病机制研究中的应用。
In syphilis research, the Nichols strain of Treponema pallidum, isolated in 1912, has been the most widely studied. Recently, important differences among T. pallidum strains emerged; therefore, we sequenced and annotated the Chicago strain genome to facilitate and encourage the use of this strain in studying the pathogenesis of syphilis.