PMR6, a Pectate Lyas>Like Gene Required for Powdely Mildew Susceptibility in Arabidopsis
PMR6, a Pectate Lyas>Like Gene Required for Powdely Mildew Susceptibility in Arabidopsis
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发表时间：
2002
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通讯作者：
J. Vogel;T. Raab;Celine Schiff;S. Somerville
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作者：
J. Vogel;T. Raab;Celine Schiff;S. Somerville
植物病原菌的生长和繁殖所需的植物基因在很大程度上是未知的。为了鉴定这些基因，我们分离了不支持白粉病病原菌白粉病的正常生长的拟南芥突变体。在这里，我们报告了其中一个基因PMR6的克隆和鉴定。PMR6编码一个带有新的C-末端结构域的果胶酶样蛋白。傅立叶变换红外光谱显示，与其预测的基因功能一致，PMR6的突变改变了植物细胞壁的组成。Pmr6介导的抗性既不需要水杨酸，也不需要感知茉莉酸或乙烯的能力，这表明抗性机制不需要激活已描述的防御途径。因此，pmr6抗性代表了一种新的基于亲和间隔期所需基因丢失的抗病形式。
The plant genes required for the growth and reproduction of plant pathogens are largely unknown. In an effort to identify these genes, we isolated Arabidopsis mutants that do not support the normal growth of the powdery mildew pathogen Erysiphe cichoracearum. Here, we report on the cloning and characterization of one of these genes, PMR6. PMR6 encodes a pectate Iyase-like protein with a novel C-terminal domain. Consistent with its predicted gene function, mutations in PMR6 alter the composition of the plant cell wall, as shown by Fourier transform infrared spectroscopy. pmr6-mediated resistance requires neither salicylic acid nor the ability to perceive jasmonic acid or ethylene, indicating that the resistance mechanism does not require the activation of well-described defense pathways. Thus, pmr6 resistance represents a novel form of disease resistance based on the loss of a gene required during a compatible inter