Maxillofacial reconstruction using custom-made artificial bones fabricated by inkjet printing technology
Maxillofacial reconstruction using custom-made artificial bones fabricated by inkjet printing technology
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DOI：
10.1007/s10047-009-0462-7
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发表时间：
2009-01-01
影响因子：
1.3
通讯作者：
Takato, Tsuyoshi
中科院分区：
文献类型：
--
作者：
Saijo, Hideto;Igawa, Kazuyo;Takato, Tsuyoshi
理想情况下，人造骨应该在尺寸上与畸形相容，并且是可生物降解的和骨传导性的;然而，迄今为止还没有开发出满足这些要求的人造骨。我们使用喷墨打印机从α-磷酸三钙粉末中制造了新型定制人工骨，并将其植入10名颌面畸形患者体内。所有患者的人工骨均具有尺寸相容性。由于最小化了尺寸调整和固定操作的需要，因此缩短了手术时间。术后计算机断层扫描分析检测到人工骨和宿主骨组织之间的部分愈合。无严重不良反应。这些发现为喷墨打印定制人工骨的进一步临床研究提供了支持。
Ideally, artificial bones should be dimensionally compatible with de formities, and be biodegradable and osteoconductive; however, there are no artificial bones developed to date that satisfy these requirements. We fabricated novel custom-made artificial bones from alpha-tricalcium phosphate powder using an inkjet printer and implanted them in ten patients with maxillofacial deformities. The artificial bones had dimensional compatibility in all the patients. The operation time was reduced due to minimal need for size adjustment and fixing manipulation. The postsurgical computed tomography analysis detected partial union between the artificial bones and host bone tissues. There were no serious adverse reactions. These findings provide support for further clinical studies of the inkjet-printed custom-made artificial bones.