Osteonecrosis of the femoral head - A prospective study with MRI
Osteonecrosis of the femoral head - A prospective study with MRI
复制标题
DOI：
10.1302/0301-620x.79b2.7179
复制
发表时间：
1997-03-01
影响因子：
--
通讯作者：
Nawada, Y
中科院分区：
文献类型：
--
作者：
Sakamoto, M;Shimizu, K;Nawada, Y
我们进行了一项前瞻性研究，使用 MRI 来评估 48 名接受大剂量皮质类固醇治疗各种自身免疫相关疾病的患者的股骨头早期坏死。从开始皮质类固醇治疗到第一次 MRI 检查的平均间隔为 2 个月（0.5 至 6）。重复MRI，平均随访时间为31个月（24至69个月）。MRI发现31个髋关节（32%）异常。最初的变化显示出界限清楚的带状区域，这些变化在开始类固醇治疗后平均 3.6 个月时出现。其中 14 个髋关节（45%）在治疗开始大约一年后，病变尺寸自发缩小，但在更长时间的随访中，病变尺寸没有进一步变化。
We performed a prospective study using MRI to evaluate early necrosis of the femoral head in 48 patients receiving high-dose corticosteroids for the treatment of various autoimmune-related disorders. The mean interval from the initiation of corticosteroid therapy to the first MRI examination was 2 months (0.5 to 6). MRI was repeated, and the mean period of follow-up was 31 months (24 to 69).Abnormalities were found on MRI in 31 hips (32%). The initial changes showed well-demarcated, band-like zones which were seen at a mean of 3.6 months after initiation of treatment with steroids. In 14 of these hips (45%) there was a spontaneous reduction in the size of the lesions about one year after treatment had started, but there was no further change in size with a longer follow-up.