Cluster Overlap Distribution Map: Visualization for Gene Expression Analysis Using Immersive Projection Technology
Cluster Overlap Distribution Map: Visualization for Gene Expression Analysis Using Immersive Projection Technology
复制标题
簇重叠分布图：使用沉浸式投影技术进行基因表达分析的可视化
DOI：
10.1162/105474603763835369
复制
发表时间：
2003
期刊：
影响因子：
--
通讯作者：
M. Hirose
中科院分区：
文献类型：
--
作者：
M. Kano;Kunihiro Nishimura;S. Tsutsumi;H. Aburatani;K. Hirota;M. Hirose
本文讨论了沉浸式投影技术（IPT）等虚拟现实技术在基因组科学领域的可能应用，并提出了面向集群的可视化技术，该技术注重多变量大型基因数据集的数据分离。基于这些策略，我们开发了聚类重叠分布图（CDCM），这是一种使用IPT对不同基因表达数据集生成的聚类集进行两两比较的可视化方法。这种方法有效地为用户提供了值得仔细检查的基因簇的指示。此外，通过使用板窗管理器系统，使用户能够在虚拟的三维空间中操作现有的2D GUI应用程序，我们开发了从提供指示到进一步检查的虚拟环境，并参考了网站上的数据库。我们的系统应用于肝细胞癌和肝母细胞瘤基因表达数据集的比较，证实了系统的有效性。
In this paper, we discuss possible applications of virtual reality technologies, such as immersive projection technology (IPT), in the field of genome science, and propose cluster-oriented visualization that attaches importance to data separation of large gene data sets with multiple variables. Based on these strategies, we developed the cluster overlap distribution map (CDCM), which is a visualization methodology using IPT for pairwise comparison between cluster sets generated from different gene expression data sets. This methodology effectively provides the user with indications of gene clusters that are worth a close examination. In addition, by using the plate window manager system, which enables the user to manipulate existing 2D GUI applications in the virtual 3D space, we developed the virtual environment for the comprehensive analysis from providing the indications to further examination by referring to the database on Web sites. Our system was applied in the comparison between the gene expression data sets of hepatocellular carcinomas and hepatoblastomas, and the effectiveness of the system was confirmed.
影响因子：
30.8
作者：
Tavazoie, S;Hughes, JD;Church, GM
通讯作者：
Church, GM